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What class of drug is danazol? It was approved by the U.S. Food and Drug Administration (FDA) as the first drug to specifically treat endometriosis, but its role as a treatment for endometriosis has been largely replaced by the gonadotropin-releasing hormone (GnRH) agonists. Danazol has antigonadotropic and anti- estrogenic activities.
Can danazol cause infertility? It can cause cysts and infertility. Danazol is a hormone that produces male characteristics as well as weight gain and acne. It does, however, relieve the painful symptoms of endometriosis, although the side effects can be unacceptable.
Does danazol increase testosterone? Danazol is a testosterone (T) derivative widely used in the clinical treatment of endometriosis. Its mechanism of action is poorly understood, but is side effects are mainly androgenic. The data suggest that many of the effects of danazol could be explained by increased levels of free T during treatment.
Does danazol cause weight gain? A single large dose of danazol is not expected to produce life-threatening symptoms. However, high doses taken over a long period of time may cause weight gain, increased acne or facial hair growth, menstrual problems, or breast changes.
How does danazol treat endometriosis? Danazol is an androgen similar to testosterone. For the treatment of endometriosis and fibrocystic breast disease, it works by decreasing the amount of hormones made by the ovaries. These hormones usually make the conditions worse.
Is armpit pain a sign of cancer? Breast cancer may be another cause of underarm swelling and pain. In its early stages, you may experience few to no symptoms. If cancer spreads outside the breast, it can affect the lymph system, and you may notice a small lump under your arm. These enlarged lymph nodes can cause discomfort.
Can fibrocystic breasts turn into cancer? No, fibrocystic breast changes don't increase your risk of breast cancer. Fibrocystic breast changes are common. Women with this noncancerous (benign) condition often have lumpy, nodular breasts and experience breast pain that varies throughout the menstrual cycle.
What are the chances of a complex breast cyst being cancerous? Complex cystic breast masses have a substantial chance of being malignant; malignancy was reported in 23% (, 1) and 31% (, 2) of cases in two series. For that reason, percutaneous or surgical biopsy is usually indicated.
When should I be concerned about breast pain? There are two main types of breast pain. Cyclical breast pain is usually worse during the week before you start your period. The pain usually subsides or improves after your period. With cyclic breast pain, it is also common to feel like your breasts are lumpier during the week before your period.
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