How is essential thrombocytosis treated? Low-dose aspirin therapy (eg, в‰¤100 mg/day) is acceptable if the ristocetin cofactor level is at least 30% in absence of other high risk factors; if it is less than 30%, all aspirin should be avoided. Hydroxyurea is generally considered the first-line drug for cytoreductive therapy in essential thrombocytosis. Can hydroxyurea cause leukemia? Hydroxyurea can cause a severe decrease in the number of blood cells in your bone marrow. This may increase the risk that you will develop a serious infection or bleeding. Hydroxyurea may increase the risk that you will develop other cancers, including skin cancer. How can you reduce cancer cells? Consider these cancer-prevention tips. Don't use tobacco. Using any type of tobacco puts you on a collision course with cancer. Eat a healthy diet. Maintain a healthy weight and be physically active. Protect yourself from the sun. Get vaccinated. Avoid risky behaviors. Get regular medical care.
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